Hospital visitors as controls in case-control studies

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Hospital visitors as controls in case-control studies.

OBJECTIVE Selecting controls is one of the most difficult tasks in the design of case-control studies. Hospital controls may be inadequate and random controls drawn from the base population may be unavailable. The aim was to assess the use of hospital visitors as controls in a case-control study on the association of organochlorinated compounds and other risk factors for breast cancer conducted...

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Smoking prevalence in neighborhood and hospital controls: implications for hospital-based case-control studies.

It is widely believed that the prevalence of smoking among hospital patients is greater than that of the general population because many conditions for which patients are hospitalized are caused by or associated with smoking, and that this increased prevalence may bias results of case-control studies of tobacco-related diseases. For this reason, many authors have suggested excluding from the co...

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Population versus hospital controls for case-control studies on cancers in Chinese hospitals

BACKGROUND Correct control selection is crucial to the internal validity of case-control studies. Little information exists on differences between population and hospital controls in case-control studies on cancers in Chinese hospital setting. METHODS We conducted three parallel case-control studies on leukemia, breast and colorectal cancers in China between 2009 and 2010, using population an...

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Hospital or population controls for case-control studies of severe childhood diseases?

There are few empirical data to determine which control group seems best in a case-control study for a severe disease: population controls or hospital controls. The author conducted a case-control study of leukemia in children using two control groups, population and hospital controls (cancers other than leukemia and severe blood diseases), between 1980 and 1993 in Québec, Canada. Maternal, pat...

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Reuse of controls in nested case-control studies.

A frequently used study design within epidemiology is large cohort studies. In some situations additional information which is not included in the cohort, for instance biological material stored in biobanks, is required. The availability of such material is usually limited and might be very expensive to analyze for the entire cohort. A reasonable strategy is therefore to restrict the study samp...

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ژورنال

عنوان ژورنال: Revista de Saúde Pública

سال: 2001

ISSN: 0034-8910

DOI: 10.1590/s0034-89102001000500005